New research shows that a poor insecticide policy has led to some unnecessary malaria cases

New research shows that a poor insecticide policy has led to some unnecessary malaria cases


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A new study on the use of insecticides on bed nets against mosquitoes has proven that thousands of people needlessly contracted malaria due to policy failure, according to an expert at University College Cork (UCC) in Ireland.

Writing in the diary The LancetProfessor Gerry Killeen, AXA Research Chair in Pathogen Ecology at UCC says the results of a large-scale trial of bed nets treated with two insecticides, rather than one, clearly show the impact such combinations can have active ingredients on. the extraordinary burden of disease caused by malaria in rural Africa.

Professor Killeen was commenting on research by Manfred Acrombessi and his team in Benin, which was also published in The Lancet.

Because mosquitoes have evolved to tolerate pyrethroids – a class of insecticides the world relies on to prevent malaria – it has been shown that children sleeping under bed nets containing only this active ingredient only get malaria once a year on the average, and their neighbors get with dual. ingredient fillers became ill at half that rate.

Professor Killeen, who wrote the commentary with Dr Seynabou Sougoufara at Keele University, says that this landmark paper proves the point that such nets with two or more insecticides should have been approved for widespread use long ago.

“By using two or more active ingredients, such combination nets can definitively kill insecticide-resistant mosquito variants before they have a chance to multiply, preventing the establishment of resistance throughout the whole mosquito community in the first place,” said Professor Killeen.

“Certainly, pyrethroids are extremely useful insecticides for public health purposes: Apart from the standard treatment for bedbugs, they are also the only class of insecticide that can be safely dispersed in the air as a repellent vapor, to protect people who live in malicious. areas when they are awake and active outside the protective range of their bed nets.

“It is not clear at the moment whether the pyrethroid resistance genie can be put back in the bottle but that is exactly why our ongoing work in collaboration with the Ifakara Institute of Health and the Sokoine University of Agriculture in Tanzania is so important,” said the Professor Killeen.

“For the future, in the hope that new insecticide combinations can be used to select for pyrethroid susceptibility traits that make it easier to protect people against mosquitoes and malaria, our team is surveying conservation areas wild in southern Tanzania right now, looking. for malaria vector mosquitoes that have escaped insecticide pressure by feeding on wild animals other than humans or livestock,” he said.

More information:
Advances in insecticide resistant malaria vector mosquitoes, The Lancet (2023). DOI: 10.1016/S0140-6736(23)00102-2

Available at University College, Cork

Quote: New research shows poor insecticide policy caused unnecessary malaria cases (2023, January 24) Retrieved January 24, 2023 from -needless.html

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